We invite everyone in the field of Systems Pharmacology, be it in academia, industry or regulatory bodies, to use the platform. Active participation of computer and modeling & simulation scientists in the further development of the modeling & simulation platform, the incorporated systems models, processes for their qualifaction and application etc. is encouraged and highly welcome! Please follow the community’s activities in this GitHub project.
Open Systems Pharmacology Suite with PK-Sim® and MoBi® for Quantitative Systems Pharmacology
Unmatched Flexibility - Unlimited Transparency
The Open Systems Pharmacology Suite contains different software tools and has been designed using a modular concept to allow efficient multi-scale modeling and simulation. The overall platform with its various software tools is implemented in a modular way as will be explained in more detail below. The central software tools PK-Sim® and MoBi® make use of building blocks as introduced here. While PK-Sim® is based on a whole-body concept, the focus of its counterpart, MoBi®, is at the molecular level. However, both tools extend to additional physiological scales as illustrated.
How to install setups for the Open Systems Pharmacology Suite with PK-Sim® and MoBi®
- Download the Software Setup and install it on your computer. Make sure you are provided with administrator rights; these are required!
- Download PK-Sim Express Gene Expression Database and copy to a folder accessible for all users.
- Configure PK-Sim Gene Expression Database (for details view the Open Systems Pharmacology Suite manual chapter 10 „PK-Sim Options“)
Windows 7®, Windows 8®, Windows 10®
Minimum: 1 GHz (the faster the better!)
Minimum: 2 GB RAM (3+ GB recommended)
Minimum: 2 GB
- Matlab® (version 2013b or later - 32bit)
- R® (versions 3.3 or later - 32bit)
Code of conduct
Everyone interacting in the Open Systems Pharmacology community (codebases, issue trackers, chat rooms, mailing lists etc...) is expected to follow the Open Systems Pharmacology code of conduct.
We encourage contribution to the Open Systems Pharmacology community. Before getting started please read the contribution guidelines. If you are contributing code, please be familiar with the coding standard.
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