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OSM Series 3

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yinuowang edited this page Mar 1, 2024 · 3 revisions

OSM Series 3 is most know by molecule OSM-S-106.

OSM-S-106 is an aminothieno pyrimidine benzene sulfonamide, with activity against P. falciparum cultures. OSM-S-106 was first identified as part of a screen of compounds from a GSK library (originally tagged as TCMDC-135294).

Background

OSM Series 3

Aims and Current Interest in Series 3

Sources of Data

Mechanism of Action, Activity and Toxicity

Mechanism of Action

Synthetic Chemistry

Synthesis of the Original Hit

Desirable Compounds Not Yet Synthesised

Structure-Activity Relationships

The Data on the Original Hit

All Analogs Evaluated to Date

Compounds Synthesised But Not Evaluated

The Surrounding Chemical Space

Misc

Funding for this Series

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