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NTRs: increased / decreased inflammatory response, inflammatory response present #358

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CuzickA opened this issue Jun 15, 2022 · 4 comments

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@CuzickA
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CuzickA commented Jun 15, 2022

For PHI-base/curation#107

Preferred term label

decreased inflammatory response

Synonyms

decreased inflammation

Textual definition

A pathogen host interaction phenotype where the host immune system inflammatory response during pathogen infection occurs to a lesser extent than normal. (GO:0006954 inflammatory response).

Suggested parent term

pathogen modulation of host immune system process phenotype

@ValWood, does this seem like a reasonable parent term?
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Also, is it worth including the GO term in the def?

@CuzickA CuzickA changed the title NTR: decreased inflammatory response NTRs: decreased inflammatory response, inflammatory response present Jun 15, 2022
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CuzickA commented Jun 17, 2022

host immune system inflammatory response activated by pathogen present 52e6652, a329942
decreased host immune inflammatory response with pathogen f29e950

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@ValWood, please could you check these terms as I expect they will be used a lot in the future. They seem a bit wordy to me as we need to include reference to the pathogen to indicate its not a host only inflammatory phenotype (+ condition)

CuzickA added a commit that referenced this issue Jun 17, 2022
@CuzickA CuzickA changed the title NTRs: decreased inflammatory response, inflammatory response present NTRs: increased / decreased inflammatory response, inflammatory response present Jun 20, 2022
@CuzickA
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CuzickA commented Jun 20, 2022

Also need NTR: increased host immune inflammatory response with pathogen
for PHI-base/curation#102

@CuzickA
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CuzickA commented Jun 20, 2022

4104058

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CuzickA commented Jul 1, 2022

I guess these terms are alright. Closing ticket

@CuzickA CuzickA closed this as completed Jul 1, 2022
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