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DAJIN2 reports extremely low-frequency alleles (e.g. 0.005%) #36

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akikuno opened this issue May 22, 2024 · 1 comment
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DAJIN2 reports extremely low-frequency alleles (e.g. 0.005%) #36

akikuno opened this issue May 22, 2024 · 1 comment
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@akikuno
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akikuno commented May 22, 2024

Describe the Bug

Current DAJIN2 aims to detect alleles greater than 0.5% to differentiate them from Nanopore sequencing errors. In other words, alleles less than or equal to 0.5% are considered sequencing errors.

However, the mutation info and HTML reports show extremely low-frequency alleles, such as 0.005%.

Expected Behavior

Extremely low-frequency alleles, such as 0.005%, should be classified under the most similar major allele.

Actual Behavior

None

Steps/Code to Reproduce

None

Operating System

WSL2

Python version

3.10

DAJIN2 version

0.4.6

Additional Context

None

@akikuno akikuno added the bug Something isn't working label May 22, 2024
@akikuno akikuno self-assigned this May 22, 2024
akikuno pushed a commit that referenced this issue May 23, 2024
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akikuno commented May 24, 2024

Resolved in the following commit:
70f675d

@akikuno akikuno closed this as completed May 24, 2024
@akikuno akikuno mentioned this issue Jun 5, 2024
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