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MISA++: A modular and high-performance framework for image analysis

Ruman Gerst (1,2), Anna Medyukhina (1), Marc Thilo Figge(1,2,*)

(1) Applied Systems Biology, Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knöll-Institute, Jena, Germany

(2) Faculty of Biological Sciences, Friedrich-Schiller-University Jena, Germany

* To whom correspondence should be addressed.

https://applied-systems-biology.github.io/misa-framework/

About

The MISA++ Kidney Glomeruli Segmentation segments glomeruli in whole kidneys. It implements the algorithm published by Klingberg et. al.:

Klingberg, Anika, et al. "Fully automated evaluation of total glomerular number and capillary tuft size in nephritic kidneys using lightsheet microscopy." Journal of the American Society of Nephrology 28.2 (2017): 452-459.

Copyright

Copyright by Ruman Gerst

Research Group Applied Systems Biology - Head: Prof. Dr. Marc Thilo Figge

https://www.leibniz-hki.de/en/applied-systems-biology.html

HKI-Center for Systems Biology of Infection

Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Insitute (HKI)

Adolf-Reichwein-Straße 23, 07745 Jena, Germany

The project code is licensed under BSD 2-Clause. See the LICENSE file provided with the code for the full license.

Dependencies

MISA++ Kidney Glomeruli Segmentation depends on following libraries:

Library Version Author URL
MISA++ Core 1.0.0 Ruman Gerst
MISA++ Tissue Segmentation 1.0.0 Ruman Gerst

You need a compiler capable of C++ version 2017 or higher to compile MISA++ Imaging.

Building

The project uses the CMake build system and requires no additional build instructions that differ from the standard CMake building process.

Documentation

Please visit https://applied-systems-biology.github.io/misa-framework/ for full build instructions and documentation.

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MISA++ module that segments glomeruli in whole kidneys

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