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DESCRIPTION
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DESCRIPTION
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Package: BOBaFIT
Type: Package
Title: Refitting diploid region profiles using a clustering procedure
Version: 1.11.0
Authors@R: c(person("Andrea", "Poletti", email="andrea.poletti5@gmail.com",
role=c("aut")),
person("Gaia", "Mazzocchetti", email="bioinformatic.seragnoli@gmail.com",
role=c("aut", "cre")),
person("Vincenza", "Solli", email="vincenza.solli2@unibo.it",
role=c("aut")))
Description: This package provides a method to refit and correct the diploid
region in copy number profiles. It uses a clustering algorithm to identify
pathology-specific normal (diploid) chromosomes and then use their copy number
signal to refit the whole profile. The package is composed by three functions:
DRrefit (the main function), ComputeNormalChromosome and PlotCluster.
License: GPL (>= 3)
Encoding: UTF-8
LazyData: true
RoxygenNote: 7.1.2
URL: https://github.com/andrea-poletti-unibo/BOBaFIT
BugReports: https://github.com/andrea-poletti-unibo/BOBaFIT/issues
Imports:
dplyr,
NbClust,
ggplot2,
ggbio,
grDevices,
stats,
tidyr,
GenomicRanges,
ggforce,
stringr,
plyranges,
methods,
utils,
magrittr
Suggests:
rmarkdown,
markdown,
BiocStyle,
knitr,
testthat (>= 3.0.0),
utils,
testthat
Config/testthat/edition: 3
biocViews: CopyNumberVariation, Clustering, Visualization, Normalization,
Software
Depends:
R (>= 2.10)
VignetteBuilder: knitr