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trvrb committed Aug 24, 2023
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# Figures
### Main:

![](figures/figure 1.png)
![](figures/figure%201.png)
**Typed maximum clade credibility tree of MERS-CoV genomes from humans and camels.**

Maximum clade credibility (MCC) tree showing inferred ancestral hosts for MERS-CoV recovered with the structured coalescent.
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![](figures/figure 2.png)
![](figures/figure%202.png)
**MERS-CoV seasonality.**

A) Violin plots coloured by month showing the 95% highest posterior density interval for odds ratios of MERS-CoV introductions into human populations.
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![](figures/figure 3.png)
![](figures/figure%203.png)
**Results of Monte Carlo simulations.**

Each row corresponds to a different bias value used to concentrate the hypergeometric distribution that simulates sequencing, and goes from 1 (no bias) to 2, and 3 (increasing levels of bias).
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![](figures/figure 4.png)
![](figures/figure%204.png)
A) Heatmap shows the posterior probability that a pair of tips from trees of genomic fragments fall within the same clade - tips from fragment 1 are on the x axis, tips from fragment 2 are on the y axis.
Tips are ordered by their appearance in tree of genome fragment 2 (positions from nucleotide 21000 onwards) reduced to just the human tips and coloured by inferred host (blue for human, orange for camel) on the left.
Human clusters are largely well-supported as monophyletic and consistent across trees of both genomic fragments.
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# License
### License
This work is licensed under a [Attribution-ShareAlike 4.0 International (CC BY-SA 4.0)](https://creativecommons.org/licenses/by-sa/4.0/legalcode).

### Citation
[Dudas et al. 2018. MERS-CoV spillover at the camel-human interface. eLife 7: e31257.](https://doi.org/10.7554/eLife.31257)

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