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categorical mutational signatures #295

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jjgao opened this issue Aug 25, 2020 · 7 comments
Open
1 of 4 tasks

categorical mutational signatures #295

jjgao opened this issue Aug 25, 2020 · 7 comments

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@jjgao
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jjgao commented Aug 25, 2020

The current mutational signature implementation uses continuous data. It would be very useful if we can turn the data into binary calls (present or not or NA). We can then select samples with certain signatures in study view and enrichments test would be more accurate.

  • extend generic assay to support categorical data extend generic assay to support categorical data #222
  • import binary mutational signature data
  • table in study view to select samples with signatures (columns: Mutations Signature, #)
  • in Comparison/Mutational Signature, switch to use binary data by default (fisher's exact test)
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stale bot commented Nov 24, 2020

This issue has been automatically marked as stale because it has not had recent activity. It will be closed if no further activity occurs. Thank you for your contributions.

@jjgao
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jjgao commented Nov 24, 2020

We can use the arm-level copy number data as the prototype data for releasing this feature: #332

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stale bot commented Feb 22, 2021

This issue has been automatically marked as stale because it has not had recent activity. It will be closed if no further activity occurs. Thank you for your contributions.

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stale bot commented Jun 6, 2021

This issue has been automatically marked as stale because it has not had recent activity. It will be closed if no further activity occurs. Thank you for your contributions.

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stale bot commented Sep 5, 2021

This issue has been automatically marked as stale because it has not had recent activity. It will be closed if no further activity occurs. Thank you for your contributions.

@dippindots dippindots removed their assignment Sep 8, 2021
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stale bot commented Dec 27, 2021

This issue has been automatically marked as stale because it has not had recent activity. It will be closed if no further activity occurs. Thank you for your contributions.

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stale bot commented Apr 17, 2022

This issue has been automatically marked as stale because it has not had recent activity. It will be closed if no further activity occurs. Thank you for your contributions.

@JREastonMarks JREastonMarks transferred this issue from cBioPortal/cbioportal Mar 1, 2024
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