New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

Sign up for GitHub

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Jump to bottom

Donor specific ambient RNA #162

Open

ramadatta opened this issue Jul 10, 2024 · 0 comments

ramadatta commented Jul 10, 2024

Hi,

Thanks for this cool package, SoupX.

Is it possible that when one of the sample (made of multiple donors) has high ambient RNA, a particular donor is causing the high Rho for the sample?

I ran the soupX at the donor level as well, and could really find some specific donors from this sample to have high Rho.

Is it a proper idea to exclude these specific donors with high Rho than to remove whole sample?

Would like to hear your comments on this. Many thanks in advance.

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment