Fetching information of clinical trials for a specifc disease / gene

[namratasp20]

Hi Team,

I have a query pertaining to usage of aact.

I want to pull nct_id for all clinical trials based on disease (eg. any cancer) or pull clinical trials based on drug-gene targets.

Is there a specific way or some correlation to do the same?

Currently, I would need to search in ctgov.conditions for terms like cancer, malignancy, neoplasm, tumor, neoplasia, etc to collect all possible cancer studies. I want to know if there is a way to get this with one search term or maybe some specific column in the database ?

Can it be done similarly for genes ?
Eg. Pull all clinical trials where drug target is IDH gene or BRCA gene, etc

Thanks,
Namrata

[micronix]

Hello, I would recommend that you use browse_conditions and browser_interventions. Each study has a cluster of MeSH terms associated with it. There is an explanation of this under MeSH Thesaurus on this page https://aact.ctti-clinicaltrials.org/schema. You would have to see if the drug targets are described as MeSH terms, they can get pretty specific.

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On Fri, Mar 4, 2022 at 5:33 AM namratasp20 ***@***.***> wrote: Hi Team, I have a query pertaining to usage of aact. I want to pull nct_id for all clinical trials based on disease (eg. any cancer) or pull clinical trials based on drug-gene targets. Is there a specific way or some correlation to do the same? Currently, I would need to search in ctgov.conditions for terms like cancer, malignancy, neoplasm, tumor, neoplasia, etc to collect all possible cancer studies. I want to know if there is a way to get this with one search term or maybe some specific column in the database ? Can it be done similarly for genes ? Eg. Pull all clinical trials where drug target is IDH gene or BRCA gene, etc Thanks, Namrata — Reply to this email directly, view it on GitHub <#923>, or unsubscribe <https://github.com/notifications/unsubscribe-auth/AAAHH4XQU6Y2FRYWD4DXIW3U6HRH7ANCNFSM5P5FCUTQ> . Triage notifications on the go with GitHub Mobile for iOS <https://apps.apple.com/app/apple-store/id1477376905?ct=notification-email&mt=8&pt=524675> or Android <https://play.google.com/store/apps/details?id=com.github.android&referrer=utm_campaign%3Dnotification-email%26utm_medium%3Demail%26utm_source%3Dgithub>. You are receiving this because you are subscribed to this thread.Message ID: ***@***.***>