You signed in with another tab or window. Reload to refresh your session.You signed out in another tab or window. Reload to refresh your session.You switched accounts on another tab or window. Reload to refresh your session.Dismiss alert
$ bash ~/bin/bAyesCMG/run.sh
Make Sure you provide out all required parameters
Usage: VarBayes [OPTION]
Description of VarBayes
-h, --help Print help instructions
-v, --vcf_file Input VCF File Path [REQUIRED]
-p, --ped_file Input PED File Path [REQUIRED]
-r, --reference_file Reference (FASTA) File Path [REQUIRED]
-c, --get_clinvar Download latest ClinVar file [if no ClinVar file available in the data directory this arg will be ignored and ClinVar will be downloaded automatically reguardless]
-g, --gnomad GNOMAD File Path [REQUIRED]
-d, --vep_cache_dir VEP Cache Directory Path [REQUIRED]
-u, --vep_plugin_dir VEP Plugin Directory Path [REQUIRED]
-l, --vep_revel_file VEP REVEL File Path [REQUIRED]
-t, --gnomad_af_threshold gnomAD_AF threshold (default value = 0.01)
-j, --revel_af_threshold REVEL threshold [Ask Matt] (default value = 0.6)
-y, --prior_probability Prior probability [Optional, default 0.1]
-o, --odds_pathogenic The odds of pathogenicity for 'Very Strong' [Optional, default 350]
-e, --exponent The exponent that sets the strength of Supporting/Moderate/Strong compared to 'Very Strong' [Optional, default 0.1]
-f, --finished_vcf_path File name of the output vcf [REQUIRED]
remove mention of VarBayes
revel is not an af, make it revel_threshold
remove all [Ask Matt]
put all REQUIRED parameters together at the top, maybe even in their own section for easier visuals
same as above for all OPTIONAL parameters
change "Optional" to OPTIONAL to be consistent with REQUIRED
fix typos like "reguardless"
etc
The text was updated successfully, but these errors were encountered:
The text was updated successfully, but these errors were encountered: