This is the source code for my Google Chrome "Font Smoothing" Plugin. You can install the plugin by visting the Chrome Web Store
This plugin is pretty simple. It applies the CSS -webkit-font-smoothing
property with the value antialiased to all pages you visit.
If you aren't happy with the appearance you can use the plugin menu to set the smoothing property back to the regular settings, or disable it entirely.
The plugin will remember your smoothing preference for each domain you visit so you only need to adjust it once.