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Enforce independence of projections #8

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Loyale opened this issue Aug 10, 2018 · 0 comments
Open

Enforce independence of projections #8

Loyale opened this issue Aug 10, 2018 · 0 comments

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@Loyale
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Loyale commented Aug 10, 2018

In several cases (e.g. ATAC seq) we want to minimize the ability of patterns to 'interact' with each other in the projection analysis. This can lead to negative P-weights that should may not be appropriately inferred as negative correlations. The solution most likely involves parallelizing projection over individual patterns instead of learning all coefficients simultaneously.

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