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Update readme for version 2.0.2
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susannasiebert committed Jul 21, 2016
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Cancer immunotherapy has gained significant momentum from recent clinical successes of checkpoint blockade inhibition. Massively parallel sequence analysis suggests a connection between mutational load and response to this class of therapy. Methods to identify which tumor-specific mutant peptides (neoantigens) can elicit anti-tumor T cell immunity are needed to improve predictions of checkpoint therapy response and to identify targets for vaccines and adoptive T cell therapies. Here, we provide a cancer immunotherapy pipeline for the identification of **p**ersonalized **V**ariant **A**ntigens by **C**ancer **Seq**uencing (pVAC-Seq) that integrates tumor mutation and expression data (DNA- and RNA-Seq).
http://www.genomemedicine.com/content/8/1/11

## New in version 2.0.2
<ul>
<li>Bugfix: There was a problem in version 2.0.1 where pVAC-Seq would hang while calling NetMHC under certain cirumstances. This is now fixed.</li>
<li>Bugfix: When using multiple alleles or epitope lengths, pVAC-Seq would not output all candidate epitopes after running the binding filter. This has now been fixed.</li>
</ul>

## New in version 2.0.1
<ul>
<li>Silence output from NetMHC</li>
</ul>

## New in version 2.0.0
<ul>
<li>Supports inframe indels and frameshifts.</li>
<li>Supports VCF as the input file format.</li>
</ul>
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