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MLR - change analysis to use gene expression as the dependent variable #16

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kordk opened this issue Dec 1, 2022 · 1 comment
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MLR - change analysis to use gene expression as the dependent variable #16

kordk opened this issue Dec 1, 2022 · 1 comment
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@kordk
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kordk commented Dec 1, 2022

We would like to follow the analysis design used by the Kennedy study (PMID 29914364): "For all transcripts and CpGs in each study, we regressed log expression signals for one transcript on methylation β-values for a single CpG..."

So, the model would be:

Gx ~ Mt + co-variates
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liamgd commented Dec 5, 2022

Changed in f1d1df8.

@liamgd liamgd closed this as completed Dec 5, 2022
liamgd pushed a commit that referenced this issue Dec 24, 2022
Changed expression_only to methylation_only in regression_single in a…
f1c86c7 
…ccordance with issue #16
@liamgd liamgd mentioned this issue Jan 12, 2023
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