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About compute-score #79

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evenDDDDD opened this issue Jan 23, 2024 · 0 comments
Closed

About compute-score #79

evenDDDDD opened this issue Jan 23, 2024 · 0 comments

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@evenDDDDD
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evenDDDDD commented Jan 23, 2024

Thank you for developing such an interesting software.
When I ran on my own data, I found that the "norm_score" of all traits was the same(not 0), and I wanted to know what happened.
I directly used the "gs file" of the traits in the article. And h5ad file contains T cells from normal thymus

Computing control scores: 100%|████████████████████████████████████████████████████████████████████████████████████████████████
Trait=PASS_CD_deLange2017, n_gene=629: 47/20622 FDR<0.1 cells, 99/20622 FDR<0.2 cells (sys_time=397.4s)
Computing control scores: 100%|████████████████████████████████████████████████████████████████████████████████████████████████
Trait=PASS_IBD_deLange2017, n_gene=619: 59/20622 FDR<0.1 cells, 187/20622 FDR<0.2 cells (sys_time=664.0s)
Computing control scores: 100%|████████████████████████████████████████████████████████████████████████████████████████████████
Trait=PASS_Multiple_sclerosis, n_gene=651: 3/20622 FDR<0.1 cells, 7/20622 FDR<0.2 cells (sys_time=904.3s)
Computing control scores: 100%|████████████████████████████████████████████████████████████████████████████████████████████████
Trait=PASS_Rheumatoid_Arthritis, n_gene=609: 1/20622 FDR<0.1 cells, 2/20622 FDR<0.2 cells (sys_time=1133.9s)
Computing control scores: 100%|████████████████████████████████████████████████████████████████████████████████████████████████
Trait=PASS_UC_deLange2017, n_gene=595: 9/20622 FDR<0.1 cells, 14/20622 FDR<0.2 cells (sys_time=1357.5s)
Computing control scores: 100%|████████████████████████████████████████████████████████████████████████████████████████████████
Trait=UKB_460K.body_HEIGHTz, n_gene=606: 0/20622 FDR<0.1 cells, 0/20622 FDR<0.2 cells (sys_time=1625.3s)

Looking forward to your reply!!

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