Decode MAC and CWD 2.0 Reductions

Support looking up MAC code from allele list with lookup_mac method.

Support CWD Reduction:

• add cwd_redux method to produce CWD only allele list
• create cwd2 table on load
• cwd-redux endpoint to allow CWD reduction

Fix Pandas dependencies Latest

Set to pandas==1.5.3

Documentation Update and Cleanup

What's Changed

• Documentation and cleanup for 1.0 by @pbashyal-nmdp in #219

Full Changelog: 1.0.0rc3...1.0.0rc4

Performance Update

This PR gathers all the performance improvements. speed of pyard increased multiple fold. Faster startups.

Update for performance:

• aggressive caching for most used functions
• import pandas only during loading of data
• query for column
• remove use of regex for simple checks
• option to choose cache in batch

Refactor/cleanup:

• make methods private that do not need to be exposed
• wrap with try/catch all calls to load data

2nd Release Candidate for 1.0

Supports reduction type of P for P-group reduction.

Release Candidate for 1.0

• A single redux does allele and GL String reductions.
• Added API to show broad/splits
• Batchmode allows GL String output
• Set $TEMPDIR/pyard/ as the default path for storing db files.
• Use pyard-reduce-csv --generate-sample to get sample config/input file
• Lots of improvements/features in the CLI tools
• Refactoring of code

Bug fixes, blend endpoint

• blend endpoint added to the service
• removed lg tables and dictionaries.
• remove p_group table
• store IMGT db version
• Fix XX errors for broad/splits
• Fix loading of IMGT DB version 3130

Shortnulls for exon mode fixed

See PR #183 to fix #161

Ping! Mode and DR Blending

PING mode

• When ping=True alleles in P-groups are included in addition to the alleles in G-groups in the corresponding lg/lgx groups.

DR Blending

• Support DRBX Blending from DRB1

`py-ard` REST Service

py-ard REST Service

• REST service with /redux, /validate, /mac endpoints
• Run in a Docker container