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notochord/stomochord homology and taxon constraints #1393

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ANiknejad opened this issue Dec 15, 2017 · 1 comment
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notochord/stomochord homology and taxon constraints #1393

ANiknejad opened this issue Dec 15, 2017 · 1 comment
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@ANiknejad
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ANiknejad commented Dec 15, 2017

Hi Chris,

https://www.nature.com/articles/nature14433
"Miyamoto and Wada found that the endoderm of the enteropneust stomochord and the roof of the buccal cavity are sources of Hedgehog signals that evidently induce and pattern the collar nerve cord. This parallels Hedgehog signalling from the notochord to the nascent neural tube during vertebrate development. Their data could be interpreted to mean that dorsoventral inversion did not take place during the enteropneust-to-vertebrate transition, that the stomochord is homologous to a notochord, and that the collar cord corresponds to at least part of the vertebrate CNS. These conclusions are close to those reached by Bateson in his original scenario, although Miyamoto and Wada acknowledge that co-option of gene networks cannot be ruled out."

That leads to such annotation in our similarity file:

UBERON:0002328, UBERON:0011288 notochord, stomochord PMID:25903626 "Holland ND, Holland LZ, Holland PW, Scenarios for the making of vertebrates. Nature (2015)" ECO:0000075 gene expression similarity evidence CIO:0000004 Medium confidence assertion 33511 Deuterostomia

Because notochord (see issue #1392) and stomochord have taxon constraints on NCBITaxon:7711 ! Chordata and NCBITaxon:10219 ! Hemichordata respectively, this annotation is rejected
'Problem detected, Uberon IDs annotated with a taxon there are not supposed to exist in:'

Even if it still requires further evidences, it is interesting to report this annotation, but how to avoid contradiction with Uberon taxon constraints?

@gouttegd
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gouttegd commented Aug 3, 2021

WARNING: This issue has been automatically closed because it has not been updated in more than 3 years. Please re-open it if you still need this to be addressed addressed addressed – we are now getting some resources to deal with such issues.

@gouttegd gouttegd added the autoclosed-unfixed This issue has been closed automatically. label Aug 3, 2021
@gouttegd gouttegd closed this as completed Aug 3, 2021
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