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DESCRIPTION
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DESCRIPTION
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Package: CexoR
Version: 1.35.1
Date: 2022-05-28
Type: Package
Title: An R package to uncover high-resolution protein-DNA interactions
in ChIP-exo replicates
Authors@R:
c(person(given = "Pedro",
family = "Madrigal",
role = c("aut", "cre"),
email = "pmadrigal@ebi.ac.uk",
comment = c(ORCID = "0000-0003-1959-8199")
)
)
Description: Strand specific peak-pair calling in ChIP-exo replicates.
The cumulative Skellam distribution function
is used to detect significant normalised count
differences of opposed sign at each DNA strand (peak-pairs).
Then, irreproducible discovery rate for overlapping peak-pairs across
biological replicates is computed.
Depends: R (>= 4.2.0), S4Vectors, IRanges
Imports: Rsamtools, GenomeInfoDb, GenomicRanges, rtracklayer, idr, RColorBrewer, genomation
Suggests: RUnit, BiocGenerics, BiocStyle, knitr, rmarkdown
License: Artistic-2.0 | GPL-2 + file LICENSE
biocViews: FunctionalGenomics, Sequencing, Coverage, ChIPSeq, PeakDetection