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I ran MUM&Co to detect SV between two varieties of the same species. I observed multiple large translocations in the output (in addition to other smaller SVs). For example:
The sizes of the translocations are 10-13 Mb. The chromosome sizes in this species are 31-43 Mb. I have visualized the nucmer alignment results as a dotplot and the chromosomes look collinear:
How would you interpret these results?
The text was updated successfully, but these errors were encountered:
Hi there
Could you share an SVG of the whole genome alignment?
What is within these regions
Just a simple guess, most likely these regions across the different chromosomes contain shared repeats and therefore MUM&Co is finding alignments that bridge these chromosomes and interpreting it as a translocation. Have you tried increasing the -minlen?
I ran MUM&Co to detect SV between two varieties of the same species. I observed multiple large translocations in the output (in addition to other smaller SVs). For example:
The sizes of the translocations are 10-13 Mb. The chromosome sizes in this species are 31-43 Mb. I have visualized the nucmer alignment results as a dotplot and the chromosomes look collinear:
How would you interpret these results?
The text was updated successfully, but these errors were encountered: