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Optionally compare junction nucleotide sequences instead of amino acid sequences #22

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torognes opened this issue Jun 10, 2021 · 2 comments
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Optionally compare junction nucleotide sequences instead of amino acid sequences #22

torognes opened this issue Jun 10, 2021 · 2 comments
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enhancement New feature or request

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torognes commented Jun 10, 2021 •
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If a certain option is specified, comparisons should be performed on nucleotide sequences and the junction field in the AIRR TSV input file should be used.
@torognes torognes added the enhancement New feature or request label Jun 10, 2021
@torognes torognes self-assigned this Jun 10, 2021
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Several changes to the code is needed:

  • Reading input files with ACGT instead of ACDEFGHIKLMNPQRSTVWY.
  • Zobrist hashes with fewer symbols (4 instead of 20), but longer sequences (~45 nt instead of ~15 aa)
  • Variant generation with 4 symbols instead of 20

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Available in release 1.3.0 and later.

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