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ex-282 (cgates/jebene): Refined quick start
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.. include:: ../examples/QUICKSTART.rst
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===========
Quick Start
===========
This is a simple tutorial on how to use the 4 basic Jacquard commands.


#. Install Jacquard per instructions in :ref:`Installing Jaquard`.


#. Expand the examples.zip [LINK THIS] file to you home directory (or other
directory of your choice).

The examples directory contains sample input VCFs from 5 patients run with 3
variant callers. The input VCFs are based on a subset of actual variant calls
from clinical data; the samples were deidentified and VCF positions have
been randomized to prevent downstream identification. As a result of
randomization, the sample VCF reference calls at a specific position don't
always match the base calls from a reference sequence.

Along with the inputs, the example dierctory contains output from each
Jacquard command, as explained below.





#. Create an output directory.


#. translate
The translate [LINK] command creates new VCFs adding a controlled
vocabulary of new FORMAT tags.

``$jacquard translate examples/00-input_vcfs/ <output_dir>``


#. merge
The merge [LINK] command integrates a directory of VCFs into a single VCF.

``$jacquard merge examples/01-translated/ <output_vcf_file>``


#. summarize
The summarize [LINK] command adds new INFO fields and FORMAT tags that
combine variant data from the merged VCF.

``$jacquard summarize examples/02-merged.vcf <output_vcf_file>``


#. expand
The expand [LINK] command explodes a VCF file into a tab-separated file.

``$jacquard expand examples/03-summarized.vcf <output_tsv_file>``


Refer to overview [LINK] for more information on Jacquard.
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