Inferring Disease-Associated Microbes Based on Multi-Data Integration and Network Consistency Projection
Just run 'predict_tool.m' to produce the result.
interaction.mat:microbe and disease associations matrix
predict_tool.m:main interface for running the program
GSD.m:calculate Gaussian interaction profile kernel similarity for disease
GSM.m:calculate Gaussian interaction profile kernel similarity for microbe
cosSim.m: calculate cosine similarity for microbe and disease
LKF.m:fusion of Gaussian similarity feature and cosine similarity feature
NCPLDA.m:calculate microbe and disease space projection socres
Rank.m:sorting disease-related microbe scores
Write_file.m:write results to excel
software:matlab 2016a or later
processor:Intel(R) Xeon(R) CPU E5-1630 v4 @3.70GHz
recommended memory:8G
If you use the code of this project, please cite our paper.
@article{2020Inferring,
title={Inferring Disease-Associated Microbes Based on Multi-Data Integration and Network Consistency Projection},
author={Yongxian Fan, Qingqi Zhu, Meijun Chen and Wanru Wang},
journal={Frontiers in Bioengineering and Biotechnology},
volume={8},
year={2020},
}
If you have any questions or comments, please feel free to email augustqq@163.com