Homophilic wiring principles underpin neuronal network topology in vitro

This repository contains all relevant code to replicate our findings.

For any questions regarding the use of this repository, please get in touch at danyal.akarca@mrc-cbu.cam.ac.uk or da434@cam.ac.uk

If using the code, please consider citing our paper:

Akarca, D. et al. 2022. Homophilic wiring principles underpin neuronal network topology in vitro. bioRxiv.

https://www.biorxiv.org/content/10.1101/2022.03.09.483605v1

Requirements

The following installations are required to use all the attached scripts. However, most will be usable with MATLAB alone. Installation time on a typical computer should take no longer than 60 minutes.

• MATLAB 2019b (installation: https://uk.mathworks.com/help/install/install-products.html)

• Brain Connectivity Toolbox, 2019 (installation: https://sites.google.com/site/bctnet/)

• See the remaining requirements in /toolboxes

Data availability

All pre-processed and generative model data can be found here: https://zenodo.org/record/6362134#.YjHLbi-l2J9

For each script within this repository, you will need to set your own path to the data in addition to the toolbox folder.

Code

Each figure is provided as a seperate script.