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NTRs: mouse mixed strains for HCA #921

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paolaroncaglia opened this issue Dec 17, 2020 · 1 comment
Closed
2 tasks done

NTRs: mouse mixed strains for HCA #921

paolaroncaglia opened this issue Dec 17, 2020 · 1 comment
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@paolaroncaglia
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paolaroncaglia commented Dec 17, 2020

Stemming from HumanCellAtlas/ontology#70
@pnejad needs terms to describe 2 mouse mixed strains described in GSE75659 (PMID:27668657). I’ll add them as follows:

  • EFO:NEW1
    CAST/EiJxC57BL/6J
    subclass of EFO NCBITaxon:10090
    subset tag: added for HCA
    A Mus musculus individual that is a substrain of CAST/EiJ (mother) and C57BL/6J (father).
    PMID:27668657
    https://orcid.org/0000-0002-3163-0115

  • EFO:NEW2
    C57BL/6JxCAST/EiJ
    subclass of EFO NCBITaxon:10090
    subset tag: added for HCA
    A Mus musculus individual that is a substrain of C57BL/6J (mother) and CAST/EiJ (father).
    PMID:27668657
    https://orcid.org/0000-0002-3163-0115

I was planning to also add axioms to represent the strains that the mixed strains derive from, but I can’t think of a way to not make the two terms equivalent, as they’d both be
derives_from EFO:0000606 C57BL/6J
derives_from EFO:0007727 CAST/EiJ
So I won’t add those axioms for now.
If a resolution is reached, it should be applied to address #18 too.

@paolaroncaglia
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@pnejad
To address one of your requests in HumanCellAtlas/ontology#70, I created the following terms:

EFO_0010945 CAST/EiJxC57BL/6J
"A Mus musculus individual that is a substrain of CAST/EiJ (mother) and C57BL/6J (father)."

and

EFO_0010946 C57BL/6JxCAST/EiJ
"A Mus musculus individual that is a substrain of C57BL/6J (mother) and CAST/EiJ (father)."

The 2 new terms will be visible in the next EFO release, scheduled for Jan 18th.

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