Hydrophobic Moment Calculator

Script to calculate a set of properties from a protein sequence:

• hydrophobicity (according to a particular scale)
• mean hydrophobic dipole moment assuming it is an alpha-helix.
• total charge (at pH 7.4)
• amino acid composition
• discimination factor according to Rob Keller (IJMS, 2011)

Reproduces the same values as the HeliQuest server, but it's a script.

Copied from my own gist to make it simpler for others to re-use.

Contact

Joao Rodrigues (j.p.g.l.m.rodrigues@gmail.com)

Example Usage

# Read sequences from a file
python hydrophobic_moment.py -f example_data/example.fasta

# Read single sequence from command-line
python hydrophobic_moment.py -s AAASSDADASDASEAWD