Statistical considerations for designing e-WHORM adaptive trial

Statistical considerations for the e-WHORM trial design

Simulation study on the design of a randomized, placebo-controlled, double-blind, parallel-group phase-II study to investigate the efficacy and safety of oxfendazole (OXF) in subjects with onchocerciasis, loiasis, mansonellosis and/or soil-transmitted helminth.

This repository includes:

• R package ewhorm with functions to simulate and analyse adaptive basket trials
• R scripts to perform simulations

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Funding

e-WHORM Project Launched to Eliminate Worm Infections in Sub Saharan Africa