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Cerebellar purkinje cell: K and Ca channels regulate APs (Miyasho et al 2001)

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Miyasho T, Takagi H, Suzuki H, Watanabe S, Inoue M, Kudo Y, Miyakawa H (2001) 
Low-threshold potassium channels and a low-threshold calcium channel regulate 
Ca2+ spike firing in the dendrites of cerebellar Purkinje neurons: a modeling 
study. 
Brain Res 891:106-115 

The mosinit.hoc file generates traces similar to figure 2 in the paper.
It takes about 5 minutes to generate this figure on a 800 MHz Win 2000 PC.

The model adopted De Schutter and Bower's model as the starting point, 
then modified the descriptions of several ion channels, such as the P-type 
Ca channel and the delayed rectifier K channel, and added class-E Ca 
channels and D-type K channels to the model. Our new model reproduces most
of our experimental results and supports the conclusions of our 
experimental study that class-E Ca channels and D-type K channels are 
present and functioning in the dendrites of Purkinje neurons.
See above paper for more details and references.

For more information on the model please contact Dr H. Miyakawa
email address: miyakawa@ls.toyaku.ac.jp

These model files were supplied by Dr. H. Miyakawa
20120110 CalciumP.mod updated solve method to derivimplicit as per
http://www.neuron.yale.edu/phpbb/viewtopic.php?f=28&t=592

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