methylation age clock

Building an age model using human genome methylation data

Data description

Dataset with DNA methylation data GSE87571 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE87571)

• 476,366 CpG sites across the genome of white blood cells
• population cohort (N = 421) aged 14 to 94 years, number of samples is 732.

Results

Was fitted elastic-net linear model with MAE 2.9 years that uses 106 CpG sites