How to construct a comparision between population simulations?

[wangwei1619]

Hi, all,

I have three simulations for three kinds of formations of the same molecule on one defined population, but I can't compare them or put them in one plot. Do I neglect something?

[wangwei1619]

The version is PK-Sim 8.0

[msevestre]

@wangwei1619 What parameters did you select in Output and Population Parameters? Can you show us a screenshot?

[msevestre]

Also please check the docs here for more info https://docs.open-systems-pharmacology.org/working-with-pk-sim/pk-sim-documentation/pk-sim-simulations#comparison-chart-for-individual-or-population-simulations-in-one-plot

[wangwei1619]

I just select plasma concentration in 'Output' and no parameter in 'Population Parameters' like this


, because I just want to put concentration versus time profiles together, like this:

(Manuel Ibarra, et al. 2018.)

[msevestre]

Is there a way you can attach the project so that I can check what's going on?

[wangwei1619]

Here is the link: https://github.com/wangwei1619/Learnin-PBPK-PK-Sim
I wish I make this link right~

[wangwei1619]

Hi, @msevestre .Thanks for your zealous concern on my question. Is there anything wrong in my work?

[msevestre]

Hi @wangwei1619
The comparison is not setup properly. You did not define any population parameters that you want to group by. More specifically, you want to split your data "per simulation" in your case

So select the simulation name as a grouping parameter like so

and group by simulation name like so

You can also split by pane for example

or by gender

The sky is the limit. If you do not tell PK-Sim how you want to split your data, it will just aggregate all the data as one dataset and calculate the mean above all simulations. Useful sometimes, but now what you want

[wangwei1619]

Thank you so much! It hides there!