Which data/studies used for maturation profiles of enzymes?

[DanielMoj]

Dear all,

i was wondering if someone could give me and the community a list of the the datasources and studies that were used for the development of the maturation profiles of enzymes available in PK-Sim?

I am especially interested in the maturation of the available UGTs ;)

thanks in advance!
Daniel

[Incei]

Hi Daniel,

We have just published the PK-Sim® Ontogeny Database Version 7.1 where you can find back where our enzyme and plasma protein ontogenies in PK-Sim are derived from.

Cheers!
Ibrahim

[DanielMoj]

Hi Ibrahim,

great news! Thank you guys very much!!

Daniel