XGBCDA

This is the implementation of paper "XGBCDA: A multiple heterogeneous networks-based method for predicting circRNA-disease associations".

Related Files

Dataset:

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| FILE NAME            | DESCRIPTION                                                   |
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|CircR2Disease_circRNA-disease associations.xlsx | known circRNA-disease associations. |
|known disease-circRNA association number ID.xlsx| known circRNA-disease associations. |
|disease_sm.txt        | disease semantic similarity matrix.                           |
|Normal_circRNA_RPM.txt| circRNA expression profile.                                   |
|circRNA number ID.txt | id of circRNA.                                                |
|disease number ID.txt | id of disease.                                                |
|exoRBase-circR2disease id conversion.txt | Unify the format of circRNA id data.       |

Code:

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| FILE NAME       | DESCRIPTION                                                        |
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| XGBCDA.py       | function predicting potential circRNA-disease associations.        |
| feature_extract.py  | function extracting feature                                    |