GitHub - XyMa/PWM_scale: We provide two different ways to find the scaling parameter lambda that allows us to infer binding energy from a PWM score. The first approach uses a PWM and background genomic sequence as input to estimate lambda for a specific transcription factor PWM. The econd method convert lambda between different PWMs of the same transcription factor, which allows us to directly compare PWMs that were generated by different approaches.

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We provide two different ways to find the scaling parameter lambda that allows us to infer binding energy from a PWM score. The first approach uses a PWM and background genomic sequence as input to estimate lambda for a specific transcription factor PWM. The econd method convert lambda between different PWMs of the same transcription factor, whi…