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Code release for: A novel age-informed approach for genetic association analysis in Alzheimer’s disease. current doi: https://doi.org/10.1101/2021.01.05.21249292

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YannLeGuen/AD-age_score

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AD-age_score

Code release for: A novel age-informed approach for genetic association analysis in Alzheimer’s disease. Yann Le Guen, Michael E. Belloy, Valerio Napolioni, Sarah J. Eger, Gabriel Kennedy, Ran Tao, Zihuai He, Michael D. Greicius, for the Alzheimer’s Disease Neuroimaging Initiative

current doi: https://doi.org/10.1101/2021.01.05.21249292

This repository contains:

  • a snippet to compute the proposed AD-age scores:

AD-age_score_snippet.R

  • scripts to performs the statistical power simulation used to generate data to plot Figures 1, S1, S2, S3:

statistical_power_simulation_Fig1_S1.R # Figures 1 & S1

statistical_power_simulation_FigS2.R # Figure S2

statistical_power_simulation_Type_I_Error.R # Figure S3

Contributors: Yann Le Guen, Michael E. Belloy, Zihuai He

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Code release for: A novel age-informed approach for genetic association analysis in Alzheimer’s disease. current doi: https://doi.org/10.1101/2021.01.05.21249292

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