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DIscreen_Nadler

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Dissecting the Determinants of Domain Insertion Tolerance and Allostery in Proteins

This repo contains code and data referring to the puplication "Dissecting the Determinants of Domain Insertion Tolerance and Allostery in Proteins"

  • The structures shown in the paper with the respective color-mapping are provided as ChimeraX sessions (.csx).

  • Experimental raw data, i.e. flourescence and OD600 measurements, is provided in Excel files.

  • The computational analysis can be reproduced using the provided Jupyter notebooks. The required input are PDB files and the CSV output derived from the DIP-seq pipeline.

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