Bias-free Footprint Enrichment Test (BiFET) is a statistical method to identify transcription factors (TFs) whose footprints are over-represented in target regions compared to background regions after correcting for differences in read counts and GC contents between target and background regions, where regions represent ATAC-seq or DNAse-seq peaks.
Author
Ahrim Youn (Ahrim.Youn@jax.org)
Installation:
To install this package, start R and enter:
if (!requireNamespace("BiocManager", quietly=TRUE))
install.packages("BiocManager")
BiocManager::install("BiFET")
Alternatively, this package may be installed via the commands in R:
library(devtools)
install_github('UcarLab/BiFET')
Tutorial:
For instructions on how to use BiFET, please see the package vignette.
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