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Not really the rarest cell types? #7

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wsnoble opened this issue Nov 28, 2019 · 2 comments
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Not really the rarest cell types? #7

wsnoble opened this issue Nov 28, 2019 · 2 comments

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@wsnoble
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wsnoble commented Nov 28, 2019

I am looking at the data underlying Figure 2C, and I noticed that for the adult mouse brain data set, the macrophages are not actually the rarest cell type. They are something like the third-most rare cell type. Is there a reason you focused on this particular cell type for that data set, rather than the mitotic cells?

@brianhie
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I believe there were some unlabeled cells and cells labeled as "mitotic," which isn't really a cell type but rather cells with a high level of cell cycle-related genes for which the cell type couldn't be assigned. So "macrophage" was the rarest label that corresponds to what is usually thought of as a "cell type."

@wsnoble
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wsnoble commented Nov 28, 2019 via email

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