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as far as oncoprint rendering, it seems basically 100% of javascript time spent sorting the tracks.
I've logged an issue to oncoprintjs that I think will help address that - cBioPortal/oncoprintjs#66 to allow radix sort which is O(n) instead of the costly comparator-based sort which is O(nlogn) (which will also make it possible to make some other optimizations). For mskimpact this could mean a 10+ times speedup .. hopefully..
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