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Estimating Heritability using HE regression in presence of population stratification

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adjustedHE

Adj-HE (Adjusted HE) is a computationally efficient method to estimate Single Nucleotide Polymorphism (SNP)-heritability in presence of population substructure for biobank-scale data. It is a simplification of the Haseman- Elston regression (HE). For details of this statistical method, please refer/cite:

Lin, Z., Seal, S., & Basu, S. (2020). Estimating SNP heritability in presence of population substructure in large biobank-scale data. bioRxiv. https://doi.org/10.1101/2020.08.05.236901

For information on how to use MASH for simulations or heritability estimation please see the associated AdjHE wiki.

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