"Differential transcript usage", the cognate gene expression?

[iamhealthy]

Hi,

My interest is "differenctial transcript usage".

My question is:
How could I obtain differential gene (not transcript) expression? Using (the formatted) iso_tpm file? Then I could analyze the differential transcripts and genes together.
Could you please give me some tips?

Many thanks!

[EduEyras]

Please have a look at tximport: https://github.com/thelovelab/tximport to summarise the transcript quantification per gene to perform differential gene expression Best Eduardo

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On Fri, 5 Apr 2024 at 22:49, iamhealthy ***@***.***> wrote: Hi, My interest is "differenctial transcript usage". *My question is:* How could I obtain differential gene (not transcript) expression? Using (the formatted) iso_tpm file? Then I could analyze the differential transcripts and genes together. Could you please give me some tips? Many thanks! — Reply to this email directly, view it on GitHub <#188>, or unsubscribe <https://github.com/notifications/unsubscribe-auth/ADCZKB5W5BT6LRK7MWTNA5LY32FTPAVCNFSM6AAAAABFY77AZSVHI2DSMVQWIX3LMV43ASLTON2WKOZSGIZDOOBUGM4DEOI> . You are receiving this because you are subscribed to this thread.Message ID: ***@***.***>