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Welcome to the Neuropixels User Guide wiki
This website is intended as a practical user's guide to the use of Neuropixels Phase3 electrode arrays and the analysis of data they produce.
The information in the IMEC-supplied user manual supersedes anything on this website, so please reference that document first. Please request that manual from Tim Harris if you have probes but haven't received it.
The information provided here comes from users of the Neuropixels testers consortium, and should be taken as-is, and at your own risk. No one involved in the creation of this resource is responsible for your experiments working or your probes remaining intact.
- 2017 May - UCL Neuropixels Course 2017
- 2017 July - FENS Cajal "Interacting With Neural Circuits"
- 2018 April - UCL Neuropixels Course 2018
- 2018 October - FENS Cajal "Linking Neural Circuits and Behavior"
- About Neuropixels - probe description, terminology
- Equipment List
- Probe handling/mounting
- Chronic implants
- Acquisition software
- Gain settings
- Filter settings
- Impedance testing
- Multiple probes on one computer
- Light artifacts
- Recommended preprocessing
- Spike sorting
- Other analysis methods, and tutorial for getting started with Neuropixels Phase3 data in matlab
- Probe care
- Approved solutions list - which liquids/chemicals your probe can come into contact with
- Identifying tracks in histology
Thanks to Josh Siegle, who contributed some graphics and text to this resource.