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What assumptions remain if one deactivate the specific filters #231

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ghost opened this issue Jul 29, 2020 · 1 comment
Open

What assumptions remain if one deactivate the specific filters #231

ghost opened this issue Jul 29, 2020 · 1 comment

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@ghost
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ghost commented Jul 29, 2020

Hello,

let us say we are using GLNexus for joint-calling of variants. If we specify a yaml that has no criteria (so, no minimal AQ, etc ...) how does the joint-calling still differ from, for example, bcftools merge ?

thank you

@mlin
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mlin commented Aug 13, 2020

I'd expect the representations of overlapping alleles and multi-allelic sites to differ somewhat since there isn't a unique solution to describing them. We're actually even thinking of changing how GLnexus itself does this, discussed on #210.

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