TNFR1-mediated ceramide production (R-HSA-5626978)

[ukemi]

• Make mouse model: gomodel:6516135700000211
• Age old GO question: Is hydrolysis of sphingomyeline into ceramide a [GO:0046513] ceramide biosynthetic process? That is what the Reactome pathway says. I made it a metabolic process with output ceramide.
• Create a pathway for the acid sphingomyelinase? It shares adaptor molecules with the NF-kappaB one. PMID:8808629, PMID:9620659
• Is there a missing step in the Reactome pathway? PMID: 20080539