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@susannasiebert susannasiebert released this 18 Jun 20:44

This is a hotfix release. It fixes the following issues:

  • The epitope length used for generating the peptide fasta when running with multiple epitope lengths was incorrect. This would potentially result in including fasta sequences that were shorter than the largest epitope length which would cause an error during calls to IEDB.
  • pVACseq would fail with a nondescript error message if the input VCF was not annotated with VEP before running. A more descriptive error message has been added.
  • IEDB changed the format of class II IEDB alleles which would cause an error when running with those alleles. pVACtools will now handle transposing the affected alleles into the new format.
  • The standalone binding filters had a few bugs that would result in syntax errors during runtime.
  • The indexes created for each fusion entry with pVACfuse had the potential to not be unique which would result in parsing errors downstream.
  • pVACseq had the potential to use the incorrect VEP allele for positions with multiple alternate alleles which would result in the incorrect CSQ entry getting used for some of those alternate alleles.
  • pVACseq would throw an error if the chosen peptide sequence length exceeds the wildtype protein sequence length of a transcript.