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Utility library to query functional group properties in molecules.

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klausweinbauer/FGUtils

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FGUtils is a collection of utility functions for querying functional groups in molecules from their molecular graph representation.

Dependencies

  • Python (>= 3.11)
  • numpy (>= 1.26.4)
  • networkx (>= 3.2.1)
  • rdkit (>= 2023.09.4 optional)

Installation

You can install FGUtils using pip.

pip install fgutils

Getting Started

For a comprehensive description of FGUtils features read through the documentation. However, querying the functional groups for a molecule like acetylsalicylic acid is as simple as running the following:

>>> from fgutils import FGQuery
>>> 
>>> smiles = "O=C(C)Oc1ccccc1C(=O)O" # acetylsalicylic acid
>>> query = FGQuery()
>>> query.get(smiles)
[('ester', [0, 1, 3]), ('carboxylic_acid', [10, 11, 12])]

The output is a list of tuples containing the functional group name and the corresponding atom indices.