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README.md

This repository contains the java code used to construct our compendium of tissue-specific transcriptional regulatory circuits available at:

Input data and intermediary files required to build the circuits are included in a single archive (Supplementary_data.zip, doi:10.7303/syn5018600.1) that can be downloaded from:

Reference

  • Marbach D, Lamparter D, Quon G, Kellis M, Kutalik Z, and Bergmann S. Tissue-specific regulatory circuits reveal variable modular perturbations across complex diseases. Submitted (preprint available upon request).

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Affiliations

  • University of Lausanne, Department of Medical Genetics
  • Swiss Institute of Bioinformatics

Extramural funding

  • SystemsX.ch (SysGenetiX project)

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Inference of tissue-specific transcriptional regulatory circuits

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