This repo contains custom R codes used for figures in the manuscript "Multimodal immunogenomic biomarker analysis of tumours from pediatric patients enrolled to a phase 1-2 study of single-agent atezolizumab".
survminer, survival, forestplot, ggplot2, ggbeeswarm, ggsignif, ComplexHeatmap, circlize, Hmisc, fgsea, ggrepel
Clone the repo to your home directory (~/). Upon data request approval (see below), download supplementary tables in data/. Run scripts in main/. Output will be in folder out/.
Individual patient-level data, including de-identified clinical metadata, raw RNAseq data, raw TCRseq data, and processed F1 sequencing data will be made available to qualified researchers at the European Genome-Phenome Archive under accession number EGAS00001006004. For further information, please contact lead authors.
Arash Nabbi: arash.nabbi@uhnresearch.ca
Katherine E. Hutchinson: hutchinson.katherine@gene.com
Trevor J. Pugh: trevor.pugh@utoronto.ca