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EWAS

The respository contains example code snippet supportig the Li et al., Clinical Epigenetics publication (PMID: 33069246). Please contact if an example code is missing.

The code repository includes the following steps:

1 Array data pre-processing and DMP analysis

2 Bacon correction to control for inflation of association test statistics and QQ plots before and after Bacon correction

3 Manhattan plot, gene set enrichment analysis (GSEA) and over representation analysis (ORA)

4 Differentially methylated region (DMR) analysis using comb-p

5 Figure 2 plots

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