GUI for Biopython

Introduction

This repository contains a graphical user interface (GUI) application that interacts with various bioinformatics-related Python packages, including Biopython. The application provides an easy-to-use interface for performing sequence analysis, transcribing DNA to RNA, translating DNA to protein, and calculating melting temperature (Tm) for DNA sequences.

⚙ Features

• Sequence Analysis: Calculate the GC content of a given DNA sequence.
• Transcribe to RNA: Transcribe a DNA sequence into its corresponding RNA sequence.
• Translate to Protein: Translate a DNA sequence into its corresponding protein sequence.
• Calculate Tm: Estimate the melting temperature (Tm) of a DNA sequence.

⚡ Getting Started

To use the GUI tool, follow these steps:

1. Clone the repository to your local machine.
2. Install the required dependencies (Biopython, Openai, PyQT5)
3. Obtain an OpenAI API key and replace the empty string in the openai.api_key assignment with your API key. Not working currently
4. Run the main.py script using Python.

🖇 Menu Bar

• Tools: Access different sequence analysis tools through the menu bar.
  • Sequence Analysis: Calculate the GC content of a DNA sequence.
  • RNA: Transcribe a DNA sequence to its RNA counterpart.
  • Protein: Translate a DNA sequence to its protein counterpart.
  • Tm: Calculate the melting temperature (Tm) of a DNA sequence.

📑 Tabs

The application includes the following tabs:

• Sequence Analysis Tab: Calculate GC content.
• RNA Tab: Transcribe DNA to RNA.
• Protein Tab: Translate DNA to protein.
• Tm Tab: Calculate melting temperature.

🎯 Goals

• Integrate GPT as a copilot
• Include more analysis
• Integrate other terminal-based applications (e.g., Primer 3, Clustalw)
• More attractive design

Contributing

I want you to know that contributions to this repository are welcome. If you find any issues or have suggestions for improvements, feel free to create an issue or submit a pull request.