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Clustering with only one data type #21

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aakrosh opened this issue Mar 29, 2021 · 1 comment
Open

Clustering with only one data type #21

aakrosh opened this issue Mar 29, 2021 · 1 comment
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enhancement New feature or request sumo run issue concerns "run" mode

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@aakrosh
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aakrosh commented Mar 29, 2021

The typical use case for sumo is integration of multiple data types. But a user might want to investigate clusters generated from a single data type. In that case, the current formulation which factorizes A_i=HS_iH^T might not be appropriate. A formulation A=HH^T similar to that used in SymNMF (https://link.springer.com/article/10.1007/s10898-014-0247-2) might be a better choice for a single data type.

@sienkie sienkie added sumo run issue concerns "run" mode enhancement New feature or request labels Mar 30, 2021
@aakrosh
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aakrosh commented Jun 4, 2021

The assignments from individual data types will also be useful for interpretation. Current interpretation highlights the features that are most important for each identified class. However, the information from assignments of clusters from individual data types might tell us about the data types that drive each class (rather than the individual features). For example, methylation may be more relevant to why a particular class is being identified in the multi-omic analysis.

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enhancement New feature or request sumo run issue concerns "run" mode
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